Kamiar Moin, Ph.D.

Wayne State University
Assistant Professor, Department of Pharmacology
Associate Director, Imaging and Cytometry Facility Core, EHS Center for Molecular & Cellular Toxicology

Tel.

(313) 577-2199

Fax.

(313) 577-6739

Email:

kmoin@med.wayne.edu

Address:

Department of Pharmacology
Wayne State University

6339 Scott Hall
Detroit, MI 48201
     
Research Interests:    
Cysteine proteases and endogenous inhibitors in progression and metastasis.
     
Select Publications:    
 

Sloane BF, Yan S, Podgorski I, Linebaugh BE, Cher ML, Mai J, Cavallo-Medved D, Sameni M, Dosescu J, Moin K. Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment. Semin Cancer Biol. 2005 Apr;15(2):149-57. Epub 2004 Dec 30. PMID: 15652460

Sameni M, Dosescu J, Moin K, Sloane BF. Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis. Mol Imaging. 2003 Jul;2(3):159-75. PMID: 14649059

Roshy S, Sloane BF, Moin K. Pericellular cathepsin B and malignant progression. Cancer Metastasis Rev. 2003 Jun-Sep;22(2-3):271-86. PMID: 12785001

Koblinski JE, Dosescu J, Sameni M, Moin K, Clark K, Sloane BF. Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B. J Biol Chem. 2002 Aug 30;277(35):32220-7. PMID: 12072442

Sameni M, Moin K, Sloane BF. Imaging proteolysis by living human breast cancer cells. Neoplasia. 2000 Nov-Dec;2(6):496-504.  PMID: 11228542

Moin K, Demchik L, Mai J, Duessing J, Peters C, Sloane BF. Observing proteases in living cells. Adv Exp Med Biol. 2000;477:391-401.  PMID: 10849765

Frosch BA, Berquin I, Emmert-Buck MR, Moin K, Sloane BF.  Molecular regulation, membrane association and secretion of tumor cathepsin B. APMIS. 1999 Jan;107(1):28-37. PMID: 10190277

Moin K, Cao L, Day NA, Koblinski JE, Sloane BF. Tumor cell membrane cathepsin B. Biol Chem. 1998 Aug-Sep;379(8-9):1093-9.  PMID: 9792442

Calkins CC, Sameni M, Koblinski J, Sloane BF, Moin K.  Differential localization of cysteine protease inhibitors and a target cysteine protease, cathepsin B, by immuno-confocal microscopy. J Histochem Cytochem. 1998 Jun;46(6):745-51.  PMID: 9603786

Seyfried D, Han Y, Zheng Z, Day N, Moin K, Rempel S, Sloane B, Chopp M. Cathepsin B and middle cerebral artery occlusion in the rat. J Neurosurg. 1997 Nov;87(5):716-23.  PMID: 9347980