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Dharam P. Chopra, Ph.D. |
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Wayne State University |
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Tel. |
(313) 961-2816 |
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Fax. |
(313) 577- 0082 |
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Email: |
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Address: |
Institute of Environmental Health Sciences
Wayne State University |
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| Research Interests: | ||
| Development of in vitro models of normal human epithelial cells, gene expression in preneoplastic and neoplastic transformation induced by chemical carcinogens. | ||
| Select Publications: | ||
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Chopra DP, Menard RE,
Januszewski J, Mattingly RR. TNF-alpha-mediated apoptosis
in normal human prostate epithelial cells and tumor cell
lines. Cancer Lett. 2004 Jan 20;203(2):145-54. PMID:
14732222
Tang S, Bhatia B, Maldonado CJ, Yang P, Newman RA, Liu J, Chandra D, Traag J, Klein RD, Fischer SM, Chopra D, Shen J, Zhau HE, Chung LW, Tang DG. Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem. 2002 May 3;277(18):16189-201. PMID: 11839751 Ben-Josef E, Yang SY, Ji TH, Bidart JM, Garde SV, Chopra DP, Porter AT, Tang DG. Hormone-refractory prostate cancer cells express functional follicle-stimulating hormone receptor (FSHR). J Urol. 1999 Mar;161(3):970-6. PMID: 10022736 Tang DG, Li L, Chopra DP, Porter AT. Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins. Cancer Res. 1998 Aug 1;58(15):3466-79. PMID: 9699682 Chopra DP, Sarkar FH, Grignon DJ, Sakr WA, Mohamed A, Waghray A. Growth of human nondiploid primary prostate tumor epithelial cells in vitro. Cancer Res. 1997 Sep 1;57(17):3688-92. PMID: 9288774 Chopra DP, Grignon DJ, Joiakim A, Mathieu PA, Mohamed A, Sakr WA, Powell IJ, Sarkar FH. Differential growth factor responses of epithelial cell cultures derived from normal human prostate, benign prostatic hyperplasia, and primary prostate carcinoma. J Cell Physiol. 1996 Nov;169(2):269-80. PMID: 8908194 Levine SJ, Logun C, Chopra DP, Rhim JS, Shelhamer JH. Protein kinase C, interleukin-1 beta, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells. Am J Respir Cell Mol Biol. 1996 Mar;14(3):254-61. PMID: 8845176 Chopra DP, Xue-Hu IC, Reddy LV. Growth and gene expression in diploid epithelial cell lines derived from normal human parotid gland. Differentiation. 1995 Feb;58(3):241-51. PMID: 7713331 Chopra DP, Reddy L, Gupta SK, Wan L, Mathieu PA, Shoemaker RL, Rhim JS. Differentiation of immortalized epithelial cells derived from cystic fibrosis airway submucosal glands. In Vitro Cell Dev Biol Anim. 1994 Aug;30A(8):539-46. PMID: 7527286 Taylor GW, Chopra DP, Mathieu PA. Differences in secretory profiles of epithelial cell cultures derived from human tracheal and bronchial mucosa and submucosal glands. Epithelial Cell Biol. 1993 Oct;2(4):163-9. PMID: 8269031 |
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