Wayne State University

Aim Higher

Core Curriculum

 

Requirements and Didactic Training for the Ph.D. Degree in the Concentration in MCT

A student enrolled in the Concentration in MCT must complete a minimum of 90 credit hours including a minimum of 30 credit hours in dissertation research, and 60 credit hours in the core curriculum and electives. The student must pass a written and an oral qualifying examination to become a Ph.D. candidate. In addition, the student must write and successfully defend a dissertation, the presentation component consisting of a seminar open to the public.

 

Academic Requirements

All students are required to maintain at least a “B” grade point average (3.0 GPA).  Should a student’s cumulative GPA drop below 3.0 in a semester; the student will be placed on academic probation for the next semester. Should a student’s GPA remain below 3.0 for more than one semester, the student will lose his/her Graduate Fellowship. Failure to raise the grade point average to the minimum 3.0 levels is grounds for dismissal from the program. A failure (grade lower than “B” or “fail”) in a Core Course may be grounds for dismissal for the program.

 

Core Curriculum

The Concentration in MCT curriculum is composed of IBS core and MCT core courses, along with elective courses to allow tailoring of individual training. All graduate students enrolled in any of the eleven PhD awarding IBS programs are required to take the IBS core courses. The IBS courses are taught by faculty from the basic science departments of the School of Medicine, and are intended to provide a sufficiently broad but comprehensive base of knowledge in the areas of cell biology, biochemistry, genetics and molecular biology. The MCT core courses are taught by IEHS faculty as well as faculty drawn from multiple WSU Colleges. The MCT courses are intended to provide a foundation in multiple aspects of toxicology. The elective courses (see below) provide the student with more detailed knowledge and laboratory experience necessary to develop sufficient expertise in the more narrowly defined specific area(s) of research that the student will be pursuing.

 

IBS core curriculum courses:

 

Course #          Course title                                           Credit hrs.            Semester

 

IBS7010            Molecular Biology                                         5                           Fall     

IBS7020            Cellular Biology                                            5                           Fall     

IBS70xx             Systems Biology                                           4                         Winter

BMS6010          Ethics in Biomedical Sciences                      1                   Spring/Summer

 

MCT Core curriculum courses:

 

Course #          Course title                                           Credit hrs.                Semester

 

MTX7010            Principles of Toxicology                             3                             Fall

MTX7500            Molecular Toxicology (Mini-course)*          3                           Winter

 

Other core courses:

 

MTX7710                         Individual Study in Molecular and Cellular Toxicology                  

MTX7700                         Current Topics in Molecular and Cellular Toxicology

MTX7890                         Seminar in Molecular and Cellular Toxicology      

MTX9990                         Pre-Dissertation Research

MTX9991 – 9994             Ph.D. Candidate Status

MTX9995                         Ph.D. Maintenance Status

 

Model Curriculum

 

Year 1

 

The first year will provide the student sufficient didactic courses, laboratory experience, and seminars to enable the student to select a Graduate Advisor and begin development of a Plan of Work.

 

FALL

Course #        Course title [Credit hrs.]

                                                                                                       

IBS7010        Molecular Biology [5]

IBS7020        Cell Biology [5]

 

Pick a laboratory for the first rotation

 

WINTER

Systems Biology (select two from the following) [4]

   IBS7030  Functional Genomics [2]

   IBS7040  Biomedical Cardiovascular, Respiratory and Renal Biology [2]

   IBS7050  Biomedical Neurobiology [2]

   IBS7060  Biomedical Endocrine Systems Biology [2]

   IBS7070  Biomedical Reproductive and Developmental Biology  [1]

   IBS7080  Biomedical Gastrointestinal Systems and Nutrition [1]

   IBS7090  Biomedical Immunology  [2]

 

Electives (please see below) [3-6]

   MTX7890           Seminars in Molecular and Cellular Toxicology [1]

   MTX7700           Current Topics in Molecular and Cellular Toxicology [1] 

 

Pick a laboratory for the second rotation

 

SPRING-SUMMER

BMS6010           Ethics in Biomedical Sciences [1]

MTX7710           Individual Studies in Molecular and Cellular Toxicology

                            (Pre-Dissertation Research-Rotations) [2-4]                  

 

                                           Total for Year 1:   23 - 27 Credit hours

 

Year 2

FALL

MTX7010          Principles of Toxicology [3]

Electives [3-6]

   MTX7890          Seminars in Molecular and Cellular Toxicology [1]

   MTX7700          Current Topics in Molecular and Cellular Toxicology [1]

   MTX9990          Pre-Dissertation Research [1-6]

                               

Select Dissertation Advisor

Prepare and Submit Plan of Work1

Select Dissertation Committee

 

WINTER

MTX7500          Molecular Toxicology (mini-courses) [3]

Electives [3-6]

   MTX 7890          Seminars in Molecular and Cellular Toxicology [1]

   MTX 7700          Current Topics in Molecular and Cellular Toxicology [1]

   MTX 9990          Pre-dissertation Research [1-6]

 

Pass written qualifying examination in March

 

SPRING-SUMMER

MTX 9990          Pre-Dissertation research [2]  

 

Prepare dissertation proposal for oral qualifying examination

Pass oral qualifying examination in August

 

                                           Total for Year 2:   24-28 Credit hours

                                           Total for Years 1 and 2:   47-55 Credit hours

 

Year 3*

FALL

MTX7890          Seminars in Molecular and Cellular Toxicology [1]

MTX7700          Current Topics in Molecular and Cellular  Toxicology [1]

MTX9991          Dissertation Research [7.5]

 

WINTER

MTX7890          Seminars in Molecular and Cellular Toxicology [1]

MTX7700          Current Topics in Molecular and Cellular Toxicology [1]

MTX9992          Dissertation Research [7.5]

 

SPRING-SUMMER

MTX7710           Individual Studies in Molecular and Cellular Toxicolgy [2]

                                                       

                                           Total for Year 3:   21 Credit hours

                                           Total for Years 1-3:   60 Course Credits

                                           Candidate status:   15 Credits

 

*BY THE END OF YEAR 3, A STUDENT MUST FINISH A TOTAL OF 60 CREDITS OF 7000 LEVEL STUDIES THAT MAY INCLUDE MTX 9990 (RESEARCH)

 

Year 4

FALL

MTX7890          Seminars in Molecular and Cellular Toxicology [1]

MTX7700          Current Topics in Molecular and Cellular Toxicology [1]

MTX9993          Dissertation Research [7.5]

 

WINTER

MTX7890          Seminars in Molecular and Cellular Toxicology [1]

MTX7700          Current Topics in Molecular and Cellular Toxicology [1]

MTX9994          Dissertation Research [7.5]

 

SPRING-SUMMER

MTX9995          Ph.D. Candidate Maintenance Status [0]

 

                                          Total for Year 4:   19 Credit hours

                                          Total for Years 1-4:   62 Course Credits

                                                                Candidate Status:   30 Credits

               

Year 5

FALL

MTX9995          Ph.D. Candidate Maintenance Status [0]               

 

WINTER       

MTX9995          Ph.D. Candidate Maintenance Status [0]

 

Year 6 (if necessary)

 

FALL

MTX9995          Ph.D. Candidate Maintenance Status [0]

 

WINTER

MTX9995          Ph.D. Candidate Maintenance Status [0]

 

The student is expected to complete and defend the doctoral dissertation during year 5. The program requires that the student will complete a minimum of sixty 7000 level credit hours by the end of year 03 and a total of ninety credit hours (60 plus 30 hrs of Ph.D. research) by the end of year 05 or the completion of the Ph.D.

 

1: Plan of Work consists of a sequence of course work and dissertation research to satisfy the requirements of the Graduate Program. The Plan of Work should be signed by the student, the advisor, and the Graduate Officer. The signed Plan of Work is then submitted to the Graduate School for approval, before the student has completed 40 graduate credits.

 

Elective courses:

 

Course #   Course title                      [Credit hrs.]  Semester

 

BMB7320       Protein Structure and Function [3] Winter

BMB7010       General Biochemistry Lecture [3] Fall

BMS6010       Ethics in Biomedical Science [1] Summer

CB8680          Molecular Mechanism - DNA Repair [3] IRR

CB7450          Tumor Immunology [3] Winter          

CB7220          Molecular Biology - Cancer Development [3] Fall

CB7210          Fundamentals of Cancer Biology [3] Winter

CB7600          Cancer Biostatistics [3] Fall

FPH7015         Biostatistics I [4] Fall

FPH7240         Epidemiology I [3] Fall

IM7010             Fundamental of Immunology [4] Winter

MGB7600        Adv. Human Genetics [3] Fall/Winter

MGB7400        Cellular Signaling [2] Fall

MGB7010        Molecular Biology & Genetics [4] Fall

PHC7010         Pharmacology Lecture [4] Winter

PHC7210         Fundamentals of Cancer Biology [4] Winter

PHC7020         Cell-Membrane Biology of Cancer [3] Winter

PSC6720         Techniques in Animal Experiments [1] Fall

PSL7640          Cell and Molecular Physiology [3] Winter

PSL7010          Graduate Physiology Lecture I [4] Fall

PSL7030          Graduate Physiology Lecture II [4] Winter

PTH7380          Cytogenetics [2] Fall

PTH7600          Molecular Pathology [3] Winter