The EACPHS building is situated in the heart of WSU's medical campus, and is close to the WSU School of Medicine, the Karmanos Cancer Center, Harper and Hutzel hospitals and clinics, Children's Hospital of Michigan, the C.S. Mott Center for Human Growth and Development and the WSU main campus. The lEHS occupies two half-floors of the EACPHS building and features all new research facilities of the open-lab design, two cell culture core facilities (one per fioor), and support facilities for cell sorting, microscopy, and advanced molecular, cellular and biochemical research. The lEHS has dedicated space for in vivo rat and mouse studies, transgenic mouse studies and xenograft investigations involving immunodeficient mouse strains. lEHS accredited in vivo animal facilities are located on the fifth floor of the EACPHS building and are directly adjacent to the WSU Division of Laboratory and Animal Resources (DLAR), which is the WSU headquarters for veterinary services. The WSU inhalation core facility is also located within IEHS research space and thus provides IEHS and P30 investigators with ready access to inhalation core facility expertise, technical resources, and equipment.
The epigenomics and proteomics core facilities are located in entirely renovated spaces in the C.S. Mott Center for Human Growth and Development and Scott Hall of the WSU School of Medicine, respectively. These facilities, which serve the entire University, are located within walking distance of lEHS. The epigenomics core facility includes (1) a space for tissue culture (BSL2) that features a state-of-the-art Nikon Eclipse Tl-E inverted microscope for photographing regular and fluorescent-labeled cell lines; (2) a workstation room for five high-end computers for analyzing and storing massive amounts of epigenomics data; and (3) a DNA preparation room that will include a FacsCalibur for bacTRAP nuclei isolation, a COPASXL embryo sorter for sorting GFP-labeled C. elegans, Drosophila, and large human cells, and a Diogenoide Bioruptor and Robotic System for large scale chromatin IP (ChIP) DNA preparations.